منابع مشابه
IER3 in pancreatic carcinogenesis
Pancreatic ductal adenocarcinoma (PDAC) has the highest mortality rate of all cancers and the lowest overall survival rate of less than 5% at 5 years. The incidence of PDAC almost equals its mortality rate and is increasing every year, with more than 10,000 predicted new cases in France, 38,000 in the United States and 65,000 in Europe [1]. PDAC is characterized by a stepwise progression of duc...
متن کاملSex steroids, carcinogenesis, and cancer progression.
The relationship between sex steroids and cancer has been studied for more than a century. Using an original intact cell analysis, we investigated sex steroid metabolism in a panel of human cancer cell lines, either hormone responsive or unresponsive, originating from human breast, endometrium, and prostate. We found that highly divergent patterns of steroid metabolism exist and that the cataly...
متن کاملExocrine Pancreatic Carcinogenesis and Autotaxin Expression
Exocrine pancreatic cancer is an aggressive disease with an exceptionally high mortality rate. Genetic analysis suggests a causative role for environmental factors, but consistent epidemiological support is scarce and no biomarkers for monitoring the effects of chemical pancreatic carcinogens are available. With the objective to identify common traits for chemicals inducing pancreatic tumors we...
متن کاملGastric cancer carcinogenesis and tumor progression.
BACKGROUND Gastric cancer (GC) remains one of the leading causes of cancer-related deaths worldwide, even though a decline has been observed in its incidence and the mortality rate in recent decades. Gastric carcinogenesis is a complex phenomena involving multiple epigenetic and genetic factors; several genetic, environmental and infectious agents interact causing a cumulative effect in the ear...
متن کاملHepatocellular Carcinoma: Carcinogenesis, Establishment, Progression, and Therapies
Hepatocellular carcinoma (HCC) has had a continuous increase worldwide in incidence over the last two decades. The development of HCC has a complicated process and correlates to numerous risk factors including hepatitis virus infection, alcoholism, food toxins, diabetes, obesity, smoking, congenital liver diseases, and errors of metabolism. Molecular links are also identified, which characteriz...
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ژورنال
عنوان ژورنال: Suizo
سال: 2007
ISSN: 0913-0071,1881-2805
DOI: 10.2958/suizo.22.3